Publications (EN)

Publications (EN)

Didier LEYS

Stroke occurring in patients with cognitive impairment or dementia. Moulin S, Leys D. Arquivos de Neuro-psiquiatria. 2017 Feb;75(2):117-121. doi: 10.1590/0004-282X20160187. Review. PMID: 28226082

Vascular Cognitive Impairment. Dichgans M, Leys D. Circ Res. 2017 Feb 3;120(3):573-591. doi: 10.1161/CIRCRESAHA.116.308426. Review. PMID: 28154105

Influence of previous physical activity on the outcome of patients treated by thrombolytic therapy for stroke. Decourcelle A, Moulin S, Sibon I, Murao K, Ronzière T, Godefroy O, Poli M, Cordonnier C, Sagnier S, Lassalle V, Okada Y, Mas JL, Bordet R, Leys D. J Neurol. 2015 Nov;262(11):2513-9. doi: 10.1007/s00415-015-7875-4. Epub 2015 Aug 15. PMID: 26275566

Influence of glycaemic control on the outcomes of patients treated by intravenous thrombolysis for cerebral ischaemia. Litke R, Moulin S, Cordonnier C, Fontaine P, Leys D. J Neurol. 2015 Nov;262(11):2504-12. doi: 10.1007/s00415-015-7874-5. Epub 2015 Aug 15. PMID: 26275565


Controlled Education of patients after Stroke (CEOPS)- nurse-led multimodal and long-term interventional program involving a patient’s caregiver to optimize secondary prevention of stroke: study protocol for a randomized controlled trial. Mendyk AM, Duhamel A, Bejot Y, Leys D, Derex L, Dereeper O, Detante O, Garcia PY, Godefroy O, Montoro FM, Neau JP, Richard S, Rosolacci T, Sibon I, Sablot D, Timsit S, Zuber M, Cordonnier C, Bordet R; on the behalf of Strokavenir network. Trials. 2018 Feb 22;19(1):137. doi: 10.1186/s13063-018-2483-0. PMID: 29471839

Role of cortical microbleeds in cognitive impairment: In vivo behavioral and imaging characterization of a novel murine model. Bergeron S, Chen Y, Auger F, Deguil J, Durieux N, Skrobala E, Barus R, Potey C, Cordonnier C, Pasquier F, Ravasi L, Bordet R, Gautier S. J Cereb Blood Flow Metab. 2018 Jan 1:271678X17752765. doi: 10.1177/0271678X17752765. [Epub ahead of print] PMID: 29333917

Transient Ischemic Attack and Minor Stroke: Definitively Not So Harmless for the Brain and Cognitive Functions. Deplanque D, Bastide M, Bordet R. Stroke. 2018 Feb;49(2):277-278. doi: 10.1161/STROKEAHA.117.020013. Epub 2018 Jan 4. PMID: 29301969

Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis? Moreau C, Danel V, Devedjian JC, Grolez G, Timmerman K, Laloux C, Petrault M, Gouel F, Jonneaux A, Dutheil M, Lachaud C, Lopes R, Kuchcinski G, Auger F, Kyheng M, Duhamel A, Pérez T, Pradat PF, Blasco H, Veyrat-Durebex C, Corcia P, Oeckl P, Otto M, Dupuis L, Garçon G, Defebvre L, Cabantchik ZI, Duce J, Bordet R, Devos D. Antioxid Redox Signal. 2018 Feb 8. doi: 10.1089/ars.2017.7493. [Epub ahead of print] PMID: 29287521

Topographic distribution of brain iron deposition and small cerebrovascular lesions in amyotrophic lateral sclerosis and in frontotemporal lobar degeneration: a post-mortem 7.0-tesla magnetic resonance imaging study with neuropathological correlates. De Reuck J, Devos D, Moreau C, Auger F, Durieux N, Deramecourt V, Pasquier F, Maurage CA, Cordonnier C, Leys D, Bordet R. Acta Neurol Belg. 2017 Dec;117(4):873-878. doi: 10.1007/s13760-017-0832-5. Epub 2017 Oct 7. PMID: 28988390

Aβ1-40 and Aβ1-42 Plasmatic Levels In Stroke: Influence of Pre-Existing Cognitive Status and Stroke Characteristics. Moulin S, Leys D, Schraen-Maschke S, Bombois S, Mendyk AM, Muhr-Tailleux A, Cordonnier C, Buee L, Pasquier F, Bordet R. Curr Alzheimer Res. 2017;14(6):686-694. PMID: 26502812

Towards the concept of disease-modifier in post-stroke or vascular cognitive impairment: a consensus report. Bordet R, Ihl R, Korczyn AD, Lanza G, Jansa J, Hoerr R, Guekht A. BMC Med. 2017 May 24;15(1):107. doi: 10.1186/s12916-017-0869-6. PMID:28539119

Cerebrovascular Lesions in Mixed Neurodegenerative Dementia: A Neuropathological and Magnetic Resonance Study. De Reuck JL, Deramecourt V, Auger F, Durieux N, Maurage CA, Pasquier F, Cordonnier C, Leys D, Bordet R. Eur Neurol. 2017;78(1-2):1-5. doi: 10.1159/000476032. Epub 2017 May 6. PMID:28478439

Frequency and topography of small cerebrovascular lesions in vascular and in mixed dementia: a post-mortem 7-tesla magnetic resonance imaging study with neuropathological correlates. De Reuck J, Auger F, Durieux N, Deramecourt V, Maurage CA, Cordonnier C, Pasquier F, Leys D, Bordet R. Folia Neuropathol. 2017;55(1):31-37. doi: 10.5114/fn.2017.66711. PMID:28430290

Neither nefopam nor acetaminophen can be used as postoperative analgesics in a rat model of ic stroke. Pétrault M, Gautier S, Bérézowski V, Ouk T, Bastide M, Pétrault O, Bordet R. Fundam Clin Pharmacol. 2017 Apr;31(2):194-200. doi: 10.1111/fcp.12246. Epub 2016 Oct 25. PMID:27689348

Lobar intracerebral haematomas: Neuropathological and 7.0-tesla magnetic resonance imaging evaluation. De Reuck J, Cordonnier C, Deramecourt V, Auger F, Durieux N, Leys D, Pasquier F, Maurage CA, Bordet R. J Neurol Sci. 2016 Oct 15;369:121-125. doi: 10.1016/j.jns.2016.08.012. Epub 2016 Aug 5. PMID:27653876

Conclusive Article: Sorting the Good from the Bad: The Different Approaches to Predict Cognitive Properties of New Symptomatic Drug Candidates for Neurodegenerative Diseases in Early Development. Deguil J, Auffret A, Schenker E, Aujard F, Lamberty Y, Bartrès-Faz D, Herrero MT, Blin O, Micallef J, Richardson JC, Bordet R. CNS Neurol Disord Drug Targets. 2016;15(7):837-8. Review. No abstract available. PMID: 27549168

Editorial: Combining Forces to Improve Alzheimer’s Disease Drug Discovery: The Symptomatic Battle. Deguil J, Auffret A, Schenker E, Aujard F, Lamberty Y, Bartrès-Faz D, Blin O, Micallef J, Richardson JC, Bordet R. CNS Neurol Disord Drug Targets. 2016;15(7):754-5. Review. No abstract available. PMID: 27549167

Influence of Medication on Fatigue Six Months after Stroke. Ponchel A, Labreuche J, Bombois S, Delmaire C, Bordet R, Hénon H. Stroke Res Treat. 2016;2016:2410921. doi: 10.1155/2016/2410921. Epub 2016 Jun 19. PMID: 27413577

The Topography of Cortical Microinfarcts in Neurodegenerative Diseases and in Vascular Dementia: A Postmortem 7.0-Tesla Magnetic Resonance Imaging Study. De Reuck JL, Auger F, Durieux N, Cordonnier C, Deramecourt V, Pasquier F, Maurage CA, Leys D, Bordet R. Eur Neurol. 2016;76(1-2):57-61. doi: 10.1159/000447297. Epub 2016 Jul 6. PMID:27379570

The incidence of post-mortem neurodegenerative and cerebrovascular pathology in mixed dementia. De Reuck J, Deramecourt V, Cordonnier C, Pasquier F, Leys D, Maurage CA, Bordet R. J Neurol Sci. 2016 Jul 15;366:164-166. doi: 10.1016/j.jns.2016.05.021. Epub 2016 May 14. PMID:27288798

Early Development of Symptomatic Drugs in AD: A Systematic Review of the Use of Biomarkers. Deguil J, Ravasi L, Lamberty Y, Auffret A, Payoux P, Leroy C, Derambure P, Bordet R. CNS Neurol Disord Drug Targets. 2016;15(7):823-36. Review. PMID:27189465

Translational Challenge Models in Support of Efficacy Studies: Effect of Cerebral Hypoxia on Cognitive Performances in Rodents. Deguil J, Ravasi L, Lanteaume L, Lamberty Y, Bordet R. CNS Neurol Disord Drug Targets. 2016;15(7):765-76. Review. PMID:27189464

Translational research on cognitive and behavioural disorders in neurological and psychiatric diseases. Corvol JC, Goni S, Bordet R; participants of the Giens XXXI, Round Table No. 1. Therapie. 2016 Feb;71(1):1-13, 15-26. doi: 10.1016/j.therap.2016.01.001. Epub 2016 Feb 3. Review. English, French. PMID:27080626

Neurobehavioral and Cognitive Changes Induced by Hypoxia in Healthy Volunteers. Lanteaume L, Cassé-Perrot C, Lefebvre MN, Audebert C, Deguil J, Auffret A, Otten L, Bartrés-Faz D, Blin O, Bordet R, Micallef J. CNS Neurol Disord Drug Targets. 2016;15(7):816-22. Review. PMID:26825090

Lipid-lowering drugs prevent neurovascular and cognitive consequences of cardiopulmonary bypass. Ouk T, Amr G, Azzaoui R, Delassus L, Fossaert E, Tailleux A, Bordet R, Modine T. Vascul Pharmacol. 2016 May;80:59-66. doi: 10.1016/j.vph.2015.12.005. Epub 2016 Jan 15. PMID:26779598

A 15-day course of donepezil modulates spectral EEG dynamics related to target auditory stimuli in young, healthy adult volunteers. Leroy C, Bourriez JL, Dujardin K, Molaee-Ardekani B, Babiloni C, Deplanque D, Ponchel A, Hennion S, Plomhause L, Devanne H, Deguil J, Payoux P, Blin O, Méligne D, Micallef J, Chauveau N, Lanteaume L, Vervueren C, Guimont F, Thalamas C, Cassé-Perrot C, Rouby F, Bordet R, Derambure P; PharmaCog Consortium. Clin Neurophysiol. 2015 Nov 27. pii: S1388-2457(15)01119-0. doi: 10.1016/j.clinph.2015.11.018. [Epub ahead of print] PMID:26699666

Detection of Cortical Microbleeds in Postmortem Brains of Patients with Lewy Body Dementia: A 7.0-Tesla Magnetic Resonance Imaging Study with Neuropathological Correlates. De Reuck JL, Auger F, Durieux N, Cordonnier C, Deramecourt V, Lebert F, Leys D, Pasquier F, Maurage CA, Bordet R. Eur Neurol. 2015;74(3-4):158-61. doi: 10.1159/000441057. Epub 2015 Oct 9. PMID:26447814

Higher neutrophil counts before thrombolysis for cerebral ischaemia predict worse outcomes. Maestrini I, Strbian D, Gautier S, Haapaniemi E, Moulin S, Sairanen T, Dequatre-Ponchelle N, Sibolt G, Cordonnier C, Melkas S, Leys D, Tatlisumak T, Bordet R. Neurology. 2015 Oct 20;85(16):1408-16. doi: 10.1212/WNL.0000000000002029. Epub 2015 Sep 11. PMID:26362283

Donepezil increases contrast sensitivity for the detection of objects in scenes. Boucart M, Bubbico G, Szaffarczyk S, Defoort S, Ponchel A, Waucquier N, Deplanque D, Deguil J, Bordet R. Behav Brain Res. 2015 Oct 1;292:443-7. doi: 10.1016/j.bbr.2015.06.037. Epub 2015 Jul 7. PMID:26162753

PPAR-Alpha Agonist Used at the Acute Phase of Experimental Ischaemic Stroke Reduces Occurrence of Thrombolysis-Induced Haemorrhage in Rats. Gautier S, Ouk T, Pétrault M, Pétrault O, Bérézowski V, Bordet R. PPAR Res. 2015;2015:246329. doi: 10.1155/2015/246329. Epub 2015 May 27. PMID:26106408

Factors Associated with Poststroke Fatigue: A Systematic Review. Ponchel A, Bombois S, Bordet R, Hénon H. Stroke Res Treat. 2015;2015:347920. doi: 10.1155/2015/347920. Epub 2015 May 25. Review. PMID:26101691

The role of PPAR activation during the systemic response to brain injury. Losey P, Ladds E, Laprais M, Geuvel B, Burns L, Bordet R, Anthony DC. J Neuroinflammation. 2015 May 22;12:99. doi: 10.1186/s12974-015-0295-7. Erratum in: J Neuroinflammation. 2017 Jul 24;14 (1):146. PMID:25994490

Which factors influence the resort to surrogate consent in stroke trials, and what are the patient outcomes in this context? Mendyk AM, Labreuche J, Henon H, Girot M, Cordonnier C, Duhamel A, Leys D, Bordet R. BMC Med Ethics. 2015 Apr 24;16:26. doi: 10.1186/s12910-015-0018-8. PMID:25903471

The significance of cortical cerebellar microbleeds and microinfarcts in neurodegenerative and cerebrovascular diseases. A post-mortem 7.0-tesla magnetic resonance study with neuropathological correlates. De Reuck JL, Deramecourt V, Auger F, Durieux N, Cordonnier C, Devos D, Defebvre L, Moreau C, Capparos-Lefebvre D, Pasquier F, Leys D, Maurage CA, Bordet R. Cerebrovasc Dis. 2015;39(2):138-43. doi: 10.1159/000371488. Epub 2015 Jan 31. PMID:25661058


Cognitive phenotypes in parkinson’s disease differ in terms of brain-network organization and connectivity. Lopes R, Delmaire C, Defebvre L, Moonen AJ, Duits AA, Hofman P, Leentjens AF, Dujardin K. Hum Brain Mapp. 2017 Mar;38(3):1604-1621. doi: 10.1002/hbm.23474. Epub 2016 Nov 17. PMID:27859960

Effects of Stimulus-Driven and Goal-Directed Attention on Prepulse Inhibition of Brain Oscillations. Annic A, Bourriez JL, Delval A, Bocquillon P, Trubert C, Derambure P, Dujardin K. Front Hum Neurosci. 2016 Jul 29;10:390. doi: 10.3389/fnhum.2016.00390. eCollection 2016. PMID:27524966

How does visuospatial attention modulate motor preparation during gait initiation? Tard C, Dujardin K, Girard A, Debaughrien M, Derambure P, Defebvre L, Delval A. Exp Brain Res. 2016 Jan;234(1):39-50. doi: 10.1007/s00221-015-4436-0. Epub 2015 Sep 10. PMID:26358126

Cognitive disorders in Parkinson’s disease: Confirmation of a spectrum of severity. Dujardin K, Moonen AJ, Behal H, Defebvre L, Duhamel A, Duits AA, Plomhause L, Tard C, Leentjens AF. Parkinsonism Relat Disord. 2015 Nov;21(11):1299-305. doi: 10.1016/j.parkreldis.2015.08.032. Epub 2015 Aug 29. PMID:26350121

Stéphanie BOMBOIS

Cerebrospinal fluid Alzheimer biomarkers can be useful for discriminating dementia with Lewy bodies from Alzheimer’s disease at the prodromal stage. Bousiges O, Bombois S, Schraen S, Wallon D, Quillard MM, Gabelle A, Lehmann S, Paquet C, Amar-Bouaziz E, Magnin E, Miguet-Alfonsi C, Delbeuck X, Lavaux T, Anthony P, Philippi N, Blanc F; ePLM network and collaborators. J Neurol Neurosurg Psychiatry. 2018 Jan 10. pii: jnnp-2017-316385. doi: 10.1136/jnnp-2017-316385. [Epub ahead of print] PMID:29321140

Relevance of Follow-Up in Patients with Core Clinical Criteria for Alzheimer Disease and Normal CSF biomarkers. Vercruysse O, Paquet C, Gabelle A, Delbeuck X, Blanc F, Wallon D, Dumurgier J, Magnin E, Martinaud O, Jung B, Bousiges O, Lehmann S, Delaby C, Quillard-Murain M, Peoc’h K, Laplanche JL, Bouaziz-Amar E, Hannequin D, Sablonniere B, Buee L, Hugon J, Schraen S, Pasquier F, Bombois S. Curr Alzheimer Res. 2018 Jan 9. doi: 10.2174/1567205015666180110113238. [Epub ahead of print] PMID:29318973


Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds: A meta-analysis. Charidimou A, Imaizumi T, Moulin S, Biffi A, Samarasekera N, Yakushiji Y, Peeters A, Vandermeeren Y, Laloux P, Baron JC, Hernandez-Guillamon M, Montaner J, Casolla B, Gregoire SM, Kang DW, Kim JS, Naka H, Smith EE, Viswanathan A, Jäger HR, Al-Shahi Salman R, Greenberg SM, Cordonnier C, Werring DJ. Neurology. 2017 Aug 22;89(8):820-829. doi: 10.1212/WNL.0000000000004259. Epub 2017 Jul 26. Review. PMID: 28747441

Stroke in women – from evidence to inequalities. Cordonnier C, Sprigg N, Sandset EC, Pavlovic A, Sunnerhagen KS, Caso V, Christensen H; Women Initiative for Stroke in Europe (WISE) group. Nat Rev Neurol. 2017 Sep;13(9):521-532. doi: 10.1038/nrneurol.2017.95. Epub 2017 Jul 21. Review. PMID: 28731036

Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis: Individual Patient Data Meta-Analysis. Charidimou A, Turc G, Oppenheim C, Yan S, Scheitz JF, Erdur H, Klinger-Gratz PP, El-Koussy M, Takahashi W, Moriya Y, Wilson D, Kidwell CS, Saver JL, Sallem A, Moulin S, Edjlali-Goujon M, Thijs V, Fox Z, Shoamanesh A, Albers GW, Mattle HP, Benavente OR, Jäger HR, Ambler G, Aoki J, Baron JC, Kimura K, Kakuda W, Takizawa S, Jung S, Nolte CH, Lou M, Cordonnier C, Werring DJ. Stroke. 2017 Jul 18. pii: STROKEAHA.116.012992. doi: 10.1161/STROKEAHA.116.012992. [Epub ahead of print] PMID: 28720659

Temporal trends in early case-fatality rates in patients with intracerebral haemorrhage. Béjot Y, Grelat M, Delpont B, Durier J, Rouaud O, Osseby GV, Hervieu-Bègue M, Giroud M, Cordonnier C. Neurology. 2017 Mar 7;88(10):985-990. doi: 10.1212/WNL.0000000000003681. Epub 2017 Feb 3. PMID: 28159886

Management of spontaneous intracerebral haemorrhages. Casolla B, Tortuyaux R, Cordonnier C. Presse Med. 2016 Dec;45(12 Pt 2):e419-e428. doi: 10.1016/j.lpm.2016.10.006. Epub 2016 Nov 2. PMID: 27816340

Cognitive status after intracerebral haemorrhage – Authors’ reply. Moulin S, Leys D, Bombois S, Cordonnier C. Lancet Neurol. 2016 Nov;15(12):1206-1207. doi: 10.1016/S1474-4422(16)30239-3. Epub 2016 Oct 11.  PMID: 27751546

Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study. Moulin S, Labreuche J, Bombois S, Rossi C, Boulouis G, Hénon H, Duhamel A, Leys D, Cordonnier C. Lancet Neurol. 2016 Jul;15(8):820-829. PMID: 27133238

Multiple Simultaneous Spontaneous Intracerebral Haemorrhages: A Rare Entity. Chen Y, Hénon H, Bombois S, Pasquier F, Cordonnier C. Cerebrovasc Dis. 2016;41(1-2):74-9. doi: 10.1159/000442475. Epub 2015 Dec 16. PMID: 26671248

Incident Cerebral Microbleeds in a Cohort of Intracerebral Haemorrhage. Pasquini M, Benedictus MR, Boulouis G, Rossi C, Dequatre-Ponchelle N, Cordonnier C. Stroke. 2016 Mar;47(3):689-94. doi: 10.1161/STROKEAHA.115.011843. Epub 2016 Feb 2. PMID: 26839348

Intracerebral hemorrhage and cognitive impairment. Xiong L, Reijmer YD, Charidimou A, Cordonnier C, Viswanathan A. Biochim Biophys Acta. 2016 May;1862(5):939-44. doi: 10.1016/j.bbadis.2015.12.011. Epub 2015 Dec 12. PMID:26692171

Prognosis and Outcome of Intracerebral Haemorrhage. Moulin S, Cordonnier C. Front Neurol Neurosci. 2015;37:182-92. doi: 10.1159/000437122. Epub 2015 Nov 12. PMID: 26587771

Prognostic Factors for Cognitive Decline After Intracerebral Hemorrhage. Benedictus MR, Hochart A, Rossi C, Boulouis G, Hénon H, van der Flier WM, Cordonnier C. Stroke. 2015 Oct;46(10):2773-8. doi: 10.1161/STROKEAHA.115.010200. Epub 2015 Aug 13. PMID: 26272386

Microbleed Status and 3-Month Outcome After Intravenous Thrombolysis in 717 Patients With Acute Ischemic Stroke. Turc G, Sallem A, Moulin S, Tisserand M, Machet A, Edjlali M, Baron JC, Leclerc X, Leys D, Mas JL, Cordonnier C, Oppenheim C. Stroke. 2015 Sep;46(9):2458-63. doi: 10.1161/STROKEAHA.115.009290. Epub 2015 Jul 30. PMID: 26230857

Diagnostic evaluation for nontraumatic intracerebral hemorrhage. Domingues R, Rossi C, Cordonnier C. Neurol Clin. 2015 May;33(2):315-28. doi: 10.1016/j.ncl.2014.12.001. Review. PMID: 25907908


Plasma amyloid levels within the Alzheimer’s process and correlations with central biomarkers. Hanon O, Vidal JS, Lehmann S, Bombois S, Allinquant B, Tréluyer JM, Gelé P, Delmaire C, Blanc F, Buée L, Touchon J, Hugon J, Vellas B, Galbrun E, Benetos A, Berrut G, Paillaud E, Wallon D, Castelnovo G, Volpe–Gillot L, Paccalin M, Robert PH, Godefroy O, Dantoine T, Camus V, Belmin J, Vandel P, Novella JL, Duron E, Rigaud AS, Schraen S*, Gabelle* on behalf of the BALTAZAR study group (2018) Alzheimers & Dementia, in press.

Plasma β-amyloid 40 levels are positively associated with mortality risks in the elderly. Gabelle A, Schraen S, Gutierrez LA, Pays C, Rouaud O, Buée L, Touchon J, Helmer C, Lambert JC, Berr C (2015) Alzheimers & Dementia, 11(6) 672-80. PMID: 25022539

David BLUM

Mutual relationship between Tau and central insulin signalling: consequences for AD and Tauopathies ? Gratuze M, Joly-Amado A, Vieau D, Buée L, Blum D. Neuroendocrinology, in press

Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of Tauopathy. Laurent C, Dorothée G, Hunot S, Martin E, Monnet Y, Duchamp M, Duong Y, Légeron FP, Leboucher A, Burnouf S, Faivre E, Carvalho K, Caillierez R, Zommer N, Demeyer D, Jouy N, Sazdovitch V, Schraen-Maschke S, Delarasse C, Buée L*, Blum D* (2017) Brain, 140(Pt 1):184-200. doi: 10.1093/brain/aww270  PMID: 27818384

Tau deletion promotes brain insulin resistance. Marciniak E, Leboucher A, Caron E, Ahmed T, Tailleux A, Dumont J, Issad T, Gerhardt E, Pagesy P, Vileno M, Bournonville C, Hamdane M, Bantubungi K, Lancel S, Demeyer D, Eddarkaoui S, Vallez E, Vieau D, Humez S, Faivre E, Grenier-Boley B, Outeiro TF, Staels B, Amouyel P, Balschun D, Buee L*, Blum D* (2017) J Exp Med, 214(8):2257-2269. doi: 10.1084/jem.20161731 PMID: 28652303

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy. Laurent C, Burnouf S, Ferry B, Batalha VL, Coelho JE, Baqi Y, Mariciniak E, Parrot S, Van der Jeugd A, Faivre E, Flaten V, Ledent C, D’Hooge R, Sergeant N, Hamdane M, Humez S, Müller CE, Lopes LV, Buée L, Blum D. Mol Psychiatr, 2016, 21(1):97-107. PMID: 25450226

Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology. Burlot MA, Braudeau J, Michaelsen-Preusse K, Potier B, Ayciriex S, Varin J, Gautier B, Djelti F, Audrain M, Dauphinot L, Fernandez-Gomez FJ, Caillierez R, Laprevote O, Bieche I, Auzeil N, Potier MC, Dutar P, Korte M, Buee L, Blum D, Cartier N (2015) Hum Mol Genet, 24(21) 5965-76. PMID: 26358780

The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory. Marciniak E, Faivre E, Dutar P, Alves Pires C, Demeyer D, Caillierez R, Laloux C, Buée L, Blum D, Humez S. Sci Rep. 2015 Oct 29;5:15862. doi: 10.1038/srep15862. PMID: 26511387


Association of plasma amyloid-ß with MRI markers of structural brain aging. Kaffashian S, Tzourio C, Soumaré A, Dufouil C, Mazoyer B, Schraen Maschke S, Buee L, Debette S (2015) Neurobiol Aging, 36(10)2663-70 PMID: 26242707

Update on Tauopathies. Lebouvier T, Pasquier F, Buée L (2017) Curr Op Neurol, 30(6):589-598. PMID: 28914736

The Chemokine MIP-1alpha/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory. Marciniak E, Faivre E, Dutar P, Alves Pires C, Demeyer D, Caillierez R, Laloux C, Buée L, Blum D, Humez S (2015) Sci Rep, 5:15862. PMID: 26511387


AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo. Domise M, Didier S, Marinangeli C, Zhao H, Chandakkar P, Buee L, Viollet B, Davies P, Marambaud P, Vingtdeux V (2016) Sci Rep, 6:26758. doi: 10.1038/srep26758. PMID: 27230293

AMPK in Neurodegenerative Diseases. Domise M, Vingtdeux V. EXS. 2016;107:153-177. Review. PMID: 27812980

AMPK in Neurodegenerative Diseases: Implications and Therapeutic Perspectives. Marinangeli C, Didier S, Vingtdeux V. Curr Drug Targets. 2016;17(8):890-907. Review. PMID: 26073858


Low Prevalence and Clinical Effect of Vascular Risk Factors in Early-Onset Alzheimer’s Disease. Chen Y, Sillaire AR, Dallongeville J, Skrobala E, Wallon D, Dubois B, Hannequin D, Pasquier F; Lille YOD study group. J Alzheimers Dis. 2017;60(3):1045-1054. doi: 10.3233/JAD-170367. PMID: 28984595

Optimization of brain perfusion image quality by cortical surface-based projection of arterial spin labeling maps in early-onset Alzheimer’s disease patients. S. Verclytte, R. Lopes, C. Delmaire, J.-C. Ferre, F. Pasquier, and X. Leclerc, Eur. Radiol., vol. 25, no. 8, pp. 2479–2484, Aug. 2015. PMID: 25744625

Cerebral Hypoperfusion and Hypometabolism Detected by Arterial Spin Labeling MRI and FDG-PET in Early-Onset Alzheimer’s Disease. S. Verclytte, R. Lopes, P. Lenfant, A. Rollin, F. Semah, X. Leclerc, F. Pasquier, and C. Delmaire, J. Neuroimaging, vol. 26, no. 2, pp. 207–212, Mar. 2016. PMID: 26031943

Renaud LOPES

Hippocampal and entorhinal cortex atrophy in post-stroke patients with cognitive impairments. C. Bournonville, A. Dufour, C. Delmaire, H. Henon, S. Bombois, C. Cordonnier, R. Bordet, and R. Lopes, Int. J. Stroke, vol. 10, pp. 376–376, Apr. 2015. PMID: 29034421

18F-FDG PET Hypometabolism patterns reflect clinical heterogeneity in sporadic forms of early-onset Alzheimer’s disease. M. Vanhoutte, F. Semah, A. Rollin, A. Jaillard, G. Kuchcinski, A. Maureille, X. Delbeuck, R. Fahmi, F. Pasquier, and R. Lopes., Neurobiology of Aging, 2017;59:184–196. PMID: 28882421


Exercise training and high-fat diet elicit endocannabinoid system modifications in the rat hypothalamus and hippocampus. Gamelin FX, Aucouturier J, Iannotti FA, Piscitelli F, Mazzarella E, Aveta T, Leriche M, Dupont E, Cieniewski-Bernard C, Leclair E, Bastide B, Di Marzo V, Heyman E. J Physiol Biochem. 2016 Aug;73(3):335-347. doi: 10.1007/s13105-017-0557-1. Epub 2017 Mar 10. Erratum in: J Physiol Biochem. 2017 Oct 5; PMID: 28283967

Acute cocoa flavanol improves cerebral oxygenation without enhancing executive function at rest or after exercise. Decroix L, Tonoli C, Soares DD, Tagougui S, Heyman E, Meeusen R. Appl Physiol Nutr Metab. 2016 Dec;41(12):1225-1232. Epub 2016 Aug 5. PMID: 27849355

Regional cerebral hemodynamic response to incremental exercise is blunted in poorly controlled patients with uncomplicated type 1 diabetes. Tagougui S, Fontaine P, Leclair E, Aucouturier J, Matran R, Oussaidene K, Descatoire A, Prieur F, Mucci P, Vambergue A, Baquet G, Heyman E. Diabetes Care. 2015 May;38(5):858-67. doi: 10.2337/dc14-1792. Epub 2015 Feb 9. PMID: 25665816

Neurotrophins and cognitive functions in T1D compared with healthy controls: effects of a high-intensity exercise. Tonoli C, Heyman E, Buyse L, Roelands B, Piacentini MF, Bailey S, Pattyn N, Berthoin S, Meeusen R. Appl Physiol Nutr Metab. 2015 Jan;40(1):20-7. doi: 10.1139/apnm-2014-0098. PMID: 25525862


The protective effect of human platelet lysate in models of neurodegenerative disease: involvement of the Akt and MEK pathways. Gouel F, Do Van B, Chou ML, Jonneaux A, Moreau C, Bordet R, Burnouf T, Devedjian JC, Devos D. J Tissue Eng Regen Med. 2017 Nov;11(11):3236-3240. doi: 10.1002/term.2222. Epub 2016 Dec 12. PMID: 27943621